C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 9/00 (2006.01) C12N 9/64 (2006.01) C12N 15/63 (2006.01) C12N 15/64 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2397839
The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
Cette invention se rapporte à de nouvelles protéines, plus spécifiquement à des molécules d'acide nucléique isolées codant ces nouveaux polypeptides. Cette invention concerne ces nouveaux polypeptides et des anticorps qui se fixent à ces polypeptides, ainsi que des vecteurs, des cellules hôtes et des procédés synthétiques et de recombinaison pour produire des polynucléotides et/ou des polypeptides et des anticorps humains. Cette invention se rapporte en outre à des procédés diagnostiques et thérapeutiques servant dans le diagnostic, le traitement, la prévention et/ou le pronostic d'affections liées à ces nouveaux polypeptides, ainsi qu'à des procédés de criblage pour identifier des agonistes et des antagonistes de ces polynucléotides et polypeptides. Cette invention concerne enfin des procédés et/ou des compositions servant à inhiber ou à stimuler la production et les fonctions de ces polypeptides.
Barash Steven C.
Rosen Craig A.
Ruben Steven M.
Barash Steven C.
Human Genome Sciences Inc.
Mbm & Co.
Rosen Craig A.
Ruben Steven M.
LandOfFree
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