Nucleic acids, proteins, and antibodies

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12N 9/64 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2393912

The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.

La présente invention concerne de nouvelles protéines et plus spécifiquement des molécules d'acide nucléique isolées qui codent de nouveaux polypeptides ; de nouveaux polypeptides et de nouveaux anticorps qui se lient à ces polypeptides ; des vecteurs, des cellules hôtes, des procédés de recombinaison et de synthèse utilisés pour produire des polynucléotides et/ou des polypeptides et des anticorps humains ; des procédés de diagnostic et de thérapie utiles pour diagnostiquer, traiter, prévenir et/ou pronostiquer des pathologies associées à ces nouveaux polypeptides ; des procédés de criblage permettant d'identifier des agonistes et des antagonistes des polynucléotides et des polypeptides selon l'invention ; des procédés et/ou des compositions qui inhibent ou stimulent la production et le fonctionnement des polypeptides selon la présente invention.

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