Nucleic sequence of the gene associated with x-linked...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2120710

L'invention concerne un fragment d'acide nucléique, caracté- risé en ce qu'il comporte une séquence nucléotidique choisie parmi: (A) la séquence SEQ ID No. 1: (B) les séquences qui en diffèrent par mutation, insertion, délétion ou substitution d'une ou plusieurs bases; (C) des fragments desdites séquences (A) et (B), (D) les séquences complémentaires desdites séquences (A), (B) et (C); et (E) les séquences qui hybrident avec les séquences (A),(B) et (C), ainsi que les séquences peptidiques correspondantes. Un frag- ment d'acide nucléique selon l'invention peut être utilisé comme amorce ou sonde, notamment dans une méthode de diagnostic d'une anomalie génétique liées au syndrome de Kallman.

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