Nucleophilic substitution process

Details Nucleophilic substitution process Nucleophilic substitution process

C - Chemistry, Metallurgy

07

D

260/322, 167/7.1

C07D 207/20 (2006.01) C07C 121/66 (1980.01)

Patent

CA 1177087

ABSTRACT OF THE DISCLOSURE Nitroaralkyl cyanides are prepared by reacting a nitroaromatic compound with an alpha,alpha- disubstituted acetonitrile in a substantially anhydrous aprotic solvent and in the presence of a base so that the nitrile undergoes a nucleophilic substitution on an unsubstituted ring carbon of the halonitro aromatic compound during which an alpha-substituent functions as a leaving group. The nitroaralkyl cyanides formed by the process can be readily converted into derivatives, such as pharmaceuticals.

414304

Affiliated with

Also associated with

Rating

Nucleophilic substitution process does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleophilic substitution process, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleophilic substitution process will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1179823