Nucleoside 5'-alkyl- or alkenylphosphate

Details Nucleoside 5'-alkyl- or alkenylphosphate Nucleoside 5'-alkyl- or alkenylphosphate

C - Chemistry, Metallurgy

07

H

260/229.1

C07H 19/04 (2006.01) C07H 19/10 (2006.01) C07H 19/20 (2006.01)

Patent

CA 1204106

ABSTRACT OF THE DISCLOSURE Nucleoside 5'-alkyl- or alkenyl phosphate compounds represented by the following formula [I] Image [I] wherein B is a purine base having a substituent or a 5-substituted uracil base, and R1 is an alkyl or alkenyl group having 14 to 26 carbon atoms, and pharmaceutically acceptable salts thereof are novel derivatives of arabinonucleosides which can have properties suitable for clinical application as antiviral agents, particularly for treating viral hepatitis.

431056

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