Nucleoside analog compositions and uses thereof

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 19/06 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2311581

The invention provides compositions that include conjugates of a carrier molecule, preferably cis-docosahexaenoic acid, and 2',3'-dideoxycytidine. The conjugates are useful in treating viral infections, especially retroviral infections, and particularly reservoirs of viral infection in peripheral T cells and central nervous system manifestations thereof.

L'invention concerne des compositions qui comprennent des conjugats d'une molécule porteuse, de préférence, de l'acide cis-docosahéxaénoïque, et du 2',3'-didéoxycytidine. Ces conjugats permettent de traiter des infections virales, en particulier, des infections rétrovirales, et en particulier, des réservoirs d'infection virales dans les lymphocytes T et les manifestations de ces infections dans le système nerveux central.

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