Nucleoside derivatives

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 19/06 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61K 31/70 (2006.01) C07D 239/46 (2006.01) C07D 405/04 (2006.01) C07D 473/00 (2006.01) C07F 9/547 (2006.01) C07F 9/6512 (2006.01) C07F 9/6558 (2006.01) C07F 9/6561 (2006.01) C07H 19/04 (2006.01) C07H 19/10 (2006.01) C07H 19/16 (2006.01) C07H 19/20 (2006.01)

Patent

CA 2093020

2093020 9206102 PCTABS00011 Novel antiviral compounds of formulae (1A) and (1B), wherein X and R1-R4 are as stated in claim 1 in the form of an .alpha.- or .beta.-anomer or a mixture thereof, and pharmaceutically acceptable salts thereof are disclosed, as well as a new method for preparation thereof. Said compounds can be used for treatment of infections caused by viruses requiring reverse transcriptase for replication, such as HIV and hepatitis B virus.

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