Nucleoside phosphoramidate prodrugs

Details Nucleoside phosphoramidate prodrugs Nucleoside phosphoramidate prodrugs

C - Chemistry, Metallurgy

07

H

C07H 19/10 (2006.01) A61K 31/7064 (2006.01) A61K 31/7076 (2006.01) A61P 31/12 (2006.01) C07H 19/04 (2006.01) C07H 19/20 (2006.01)

Patent

CA 2682230

Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure: Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula (I).

L'invention concerne des promédicaments de phosphoramidate de dérivés de nucléoside pour le traitement d'infections virales chez les mammifères, qui sont un composé, son stéréo-isomère, un sel (sel d'addition acide ou basique), un hydrate, un solvate, ou une forme cristalline de celui-ci, représentés par la structure suivante : l'invention concerne également des procédés de traitement, des utilisations et des processus de préparation utilisant chacun le composé représenté par la formule (I).

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