Nucleoside triphosphate diphosphohydrolase and uses thereof

Details Nucleoside triphosphate diphosphohydrolase and uses thereof Nucleoside triphosphate diphosphohydrolase and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 9/14 (2006.01) A61K 38/46 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 15/55 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2498651

The present invention relates to a new ectohydroxynucleotidase, namely the NTPDasse8, which allows to regulate platelet aggregation or activation involved in the formation of thrombosis and related diseases. The nucleic acid sequence and the corresponding amino acid sequence and uses thereof are described.

La présente invention concerne une nouvelle ectohydroxynucléotidase, appelée NTPDase8, permettant de réguler l'agrégation ou l'activation plaquettaire impliquée dans la formation de thromboses et de maladies associées. L'invention concerne également la séquence d'acides nucléiques et la séquence d'acides aminés correspondante et des utilisations associées.

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