Nucleotide analogs with six membered rings

Details Nucleotide analogs with six membered rings Nucleotide analogs with six membered rings

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C07D 405/04 (2006.01) C07D 495/04 (2006.01) C07H 19/06 (2006.01) C07H 19/10 (2006.01) C07H 19/16 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2463719

The present invention is related to compounds comprising six-membered rings capable of being incorporated into nucleic acids. Particularly, the six membered ring is a derivative of cyclohexane, cyclohexene, tetrahydropyran, tetrahydrothiopyran or piperidine. These compounds may be used to build up oligomeric compounds. The invention is further related to uses of these oligomeric compounds for hybridization and as probes. In addition, methods for the detection of nucleic acids are provided wherein the aligomeric compounds are used.

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