Nucleotide and amino acid sequences of hypervariable region...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/51 (2006.01) A61K 39/29 (2006.01) A61K 39/42 (2006.01) C07K 7/06 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2221313

The nucleotide and deduced amino acid sequences of hypervariable region 1 of the envelope 2 gene of 49 isolates of hepatitis C are disclosed. The invention relates to the use of these sequences to design proteins and nucleic acid sequences useful in diagnostic methods and vaccines.

L'invention porte sur un nucléotide et les séquences d'acides aminés déduites de la région 1 hypervariable du gène E2 de 49 isolats du virus de l'hépatite C, et également sur l'utilisation de ces séquences pour concevoir des protéines et des séquences d'acide nucléique utilisables dans des méthodes de diagnostics et dans des vaccins.

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