Nucleotide and amino acid sequences of the envelope 1 and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/51 (2006.01) A61K 31/70 (2006.01) A61K 39/29 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/576 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2197569

The nucleotide and deduced amino acid sequences of cDNAs encoding the envelope (1) genes and core genes of isolates of hepatitis C virus (HCV) are disclosed. The invention relates to the oligonucleotides, peptides and recombinant envelope (1) and core proteins derived from these sequences and their use in diagnostic methods and vaccines.

Séquences nucléotidiques et d'aminoacides déduites d'ADNc codant des gènes d'enveloppe 1 et des gènes noyaux d'isolats du virus de l'hépatite C (HCV). L'invention porte sur des oligonucléotides, des peptides et des protéines d'enveloppe 1 et noyaux de recombinaison dérivés de ces séquences et sur leur utilisation pour des méthodes diagnostiques et des vaccins.

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