Nucleotide derivative

Details Nucleotide derivative Nucleotide derivative

C - Chemistry, Metallurgy

07

H

260/210, 260/229

C07H 19/10 (2006.01) C07H 21/00 (2006.01) C07H 23/00 (2006.01)

Patent

CA 1260930

ABSTRACT OF THE DISCLOSURE A nucleotide of the formula [IV] shown below: Image [IV] wherein: X is hydrogen or -CO-(CH2)n-CO-R3; each of m and n is an integer up to 20; R0 is a protective group of a phosphoric acid group, R1 is hydrogen or a protective group for a 5'-hydroxyl group, R2 is hydrogen or a protective group for an amino group, R3 is a carrier having an amino group as the func- tional group and bound at this functional group in this compound, Y is oxygen atom (-O-) or an imino group (-NH-). This nucleotide, when the X is -CO-(CH2)n-CO- R3, has a carrier (R3) through a spacer (-CO-(CH2)m- CO-) on extension from the amino group of deoxy- cytidine and therefore can be used as the starting material, namely the resin, for synthesizing a 3'- aminated oligonucleotide according to the solid phase method.

494505

Affiliated with

Also associated with

Rating

Nucleotide derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleotide derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleotide derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1196255