C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07K 14/285 (2006.01) C07K 16/12 (2006.01) C07K 16/40 (2006.01) C12N 9/00 (2006.01) C12N 15/52 (2006.01) C12N 15/74 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2218741
The present invention provides the sequencing of the entire genome of Haemophilus influenzae Rd, SEQ ID NO:1. The present invention further provides the sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use. In addition to the entire genomic sequence, the present invention identifies over 1700 protein encoding fragments of the genome and identifies, by position relative to a unique Not I restriction endonuclease site, any regulatory elements which modulate the expression of the protein encoding fragments of the Haemophilus genome.
La présente invention porte sur le séquençage de la totalité du génome d'Haemophilus influenzae Rd, SEQ ID NO.1. Elle concerne également les données de séquençage enregistrées sur support informatique, ainsi que les systèmes informatiques et les procédés facilitant son utilisation. Outre la totalité de la séquence génomique, plus de 1700 fragments à codage protéique du génome sont identifiés. Est également identifié de par son positionnement par rapport à un site à enzyme de restriction Not I, tout élément régulateur qui module l'expression des fragments à codage protéique du génome Haemophilus.
Adams Mark D.
Fleischmann Robert D.
Smith Hamilton O.
Venter J. Craig
White Owen
Human Genome Sciences Inc.
Mbm & Co.
The Johns Hopkins University
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