Nucleotide sequences for novel protein tyrosine phosphatases

Details Nucleotide sequences for novel protein tyrosine phosphatases Nucleotide sequences for novel protein tyrosine phosphatases

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C07K 16/40 (2006.01) C12N 9/16 (2006.01) C12Q 1/42 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2170515

The invention relates to the cloning of two novel protein tyrosine phosphatases. Nucleic acid sequences encoding these phosphatases (PTPL1 and GLM-2) as well as anti-sense sequences also are provided. The recombinantly produced PTPL1 and GLM-2 proteins also are provided, as well as antibodies to these proteins. Methods relating to isolating the phosphatases, using the nucleic acid sequences, and using the phosphatases also are provided.

Cette invention concerne le clonage de deux nouvelles tyrosine-phosphatases protéiques, des séquences d'acides nucléiques codant ces phosphatases (PTPL1 et GLM-2), ainsi que des séquences anti-sens. Les protéines PTPL1 et GML-2 produites par recombinaison sont également décrites, ainsi que les anticorps dirigés contre ces protéines. Des procédés permettant d'isoler ces phosphatases, d'utiliser ces séquences d'acides nucléiques et ces phosphatases sont également décrits.

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