C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/20 (2006.01) C07H 19/14 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2727709
The present invention relates generally to labeled and unlabled cleavable terminating groups and methods for DNA sequencing and other types of DNA analysis. More particularly, the invention relates in part to nucleotides and nucleosides with chemically cleavable, photocleavable, enzymatically cleavable, or non- photocleavable groups and methods for their use in DNA sequencing and its application in biomedical research.
Cette invention concerne, de manière générale, des groupes de terminaison clivables, marqués et non marqués, et des procédés pour le séquençage de l'ADN et autres types d'analyses de l'ADN. Plus particulièrement, cette invention concerne en partie des nucléotides et des nucléosides ayant des groupes chimiquement clivables, photoclivables, clivables par voie enzymatique, ou non photoclivables et des procédés pour leur utilisation dans le séquençage de l'ADN et leur application en recherche biomédicale.
Hersh Megan N.
Litosh Vladislav A.
Metzker Michael L.
Stupi Brian P.
Wu Weidong
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Lasergen Inc.
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