Nucleotidic sequence regulating the initiation of transcription

C - Chemistry – Metallurgy – 12 – N

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C12N 15/76 (2006.01) C07K 7/06 (2006.01) C07K 14/36 (2006.01) C12N 1/21 (2006.01) C12N 15/11 (2006.01) C12N 15/31 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2090010

2090010 9204452 PCTABS00110 L'invention concerne une séquence nucléotidique recombinante caractérisée en ce qu'elle comprend: une séquence régulatrice de l'initiation de transcription, cette séquence régulatrice comportant un promoteur en association avec le motif GCACTC 9N GAGTGC, dans lequel "N" signifie l'une quelconque des 4 bases thymine, guanine, adénine et cytosine; une séquence codant pour un polypeptide, dit "polypeptide heterologue" autre que celle naturellement associée avec ledit promoteur; ladite séquence codante étant positionnée en aval de ladite séquence régulatrice de l'initiation de transcription, à un site qui, dans des conditions appropriées, permettrait l'expression du polypeptide sous le contrôle dudit promoteur.

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