Nusap, a novel gene encoding a tissue-specific nuclear...

Details Nusap, a novel gene encoding a tissue-specific nuclear... Nusap, a novel gene encoding a tissue-specific nuclear...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/59 (2006.01) A61K 31/7105 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/10 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2401887

The invention relates to a eukaryotic nuclear protein NuSAP which is highly expressed in proliferation tissues. More specifically, NuSAP is downregulated in developing bone. NuSAP has a discrete localization in the nucleus. The localization and the expression profile indicate its role in important biological processes such as embryologic development, cell, proliferation, DNA replication and recombination. Its function relates to diseases of the immune system and diseases of the reproductive organs in particular and cancer in general.

L'invention concerne une protéine nucléaire eucaryote NuSAP dont l'expression est extrêmement élevée dans des tissus prolifératifs. Plus particulièrement, NuSAP est régulé négativement dans des os en développement. NuSAP possède une localisation discrète dans le nucleus. Son profil de localisation et d'expression indique son rôle dans des processus biologiques importants, tels que le développement embryonnaire, la prolifération cellulaire, la réplication et la recombinaison d'ADN. Sa fonction est reliée à des maladies du système immunitaire et à des maladies des organes reproductifs, en particulier, et au cancer en général.

Affiliated with

Also associated with

Rating

Nusap, a novel gene encoding a tissue-specific nuclear... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nusap, a novel gene encoding a tissue-specific nuclear..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nusap, a novel gene encoding a tissue-specific nuclear... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1379739