Nyasol and analogs thereof for the treatment of estrogen...

A - Human Necessities – 61 – K

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A61K 31/7034 (2006.01) A61K 31/05 (2006.01) A61K 31/085 (2006.01) A61K 31/185 (2006.01) A61P 5/30 (2006.01) C07C 37/20 (2006.01) C12N 15/00 (2006.01) C12N 15/67 (2006.01)

Patent

CA 2727520

Estrogenic compositions comprising nyasol and analogs thereof are provided. Also provided are methods of using said extracts to achieve an estrogenic effect, especially in a human, e.g. a female human. In some embodiments, the methods include treatment of climacteric symptoms. In some embodiments, the methods include treatment of estrogen receptor positive cancer, such as estrogen responsive breast cancer. In some embodiments, the methods include treatment or prevention of osteoporosis.

L'invention porte sur des compositions d'oestrogènes comprenant le nyasol et ses analogues. L'invention porte également sur des procédés d'utilisation desdits extraits pour obtenir un effet oestrogénique, notamment chez un être humain, par exemple, une femme. Dans certains modes de réalisation, les procédés comprennent le traitement de symptômes climatères. Dans certains modes de réalisation, les procédés comprennent le traitement d'un cancer positif au récepteur des oestrogènes, tel qu'un cancer du sein sensible aux oestrogènes. Dans certains modes de réalisation, les procédés comprennent le traitement ou la prévention de l'ostéoporose.

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