O-alkylated rapamycin derivatives and their use,...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 498/18 (2006.01) A61K 31/436 (2006.01)

Patent

CA 2476257

The present invention is directed to novel 0-alkylated derivatives of rapamycin of formula (I), especially 40-0-alkylated derivatives, are found to have pharmaceutical utility, particularly as an immunosuppressants.

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