O-carbamoyl-(d)-phenylalanilol compounds and process for...

Details O-carbamoyl-(d)-phenylalanilol compounds and process for... O-carbamoyl-(d)-phenylalanilol compounds and process for...

C - Chemistry, Metallurgy

07

C

C07C 271/12 (2006.01) C07C 269/04 (2006.01) C07C 271/24 (2006.01) C07D 295/205 (2006.01) C07D 295/215 (2006.01)

Patent

CA 2212326

The present invention relates to O-carbamoyl-(D)--phenylalaninol compound represented by structural formula (V) and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system, wherein R1 and R2 may be the same with or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 8 carbon atoms, and to 7-membered aliphatic cyclic compounds which may comprise not more than two nitrogen or oxygen atoms directly unconnected, the total number of carbon atom of R1 and R2 ranging from 0 to 16.

La présente invention concerne un composé de O-carbamyl-(D)-phénylalanilol représenté par la formule générale (V) et des sels de ce composé pharmaceutiquement acceptables. Ce composé et ses sels sont destinés au traitement d'affections du système nerveux central. Dans cette formule générale, R<1> et R<2> peuvent être identiques entre eux ou différents l'un de l'autre. R<1> et R<2> sont choisis indépendamment dans le groupe constitué de l'hydrogène, de l'alkyle inférieur portant 1 à 8 atomes de carbone et des composés cycliques aliphatiques à 5 ou 7 branches, sans pouvoir comporter plus de deux atomes d'azote ou d'oxygène directement non reliés, le nombre total des atomes de carbone de R<1> et R<2> étant compris dans une plage allant de 0 à 16.

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