O-desmethylvenlafaxine and bazedoxifene combination product...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/137 (2006.01) A61K 31/404 (2006.01) A61K 31/55 (2006.01) A61P 5/24 (2006.01) A61P 25/00 (2006.01) C07C 215/64 (2006.01) C07D 209/12 (2006.01)

Patent

CA 2601898

A combination product containing at least two active compounds, O- desmethylvenlafaxine or a pharmaceutically acceptable salt thereof and bazedoxifene or a pharmaceutically acceptable salt thereof is described. Also described are methods of making and using this combination product to treat a variety of conditions associated with low circulating estrogen levels or low estrogen receptor activity.

Cette invention concerne un produit combiné contenant au moins deux composés actifs, l'O-desméthylvenlafaxine ou un sel pharmaceutiquement acceptable de celle-ci et la bazedoxifène ou un sel pharmaceutiquement acceptable de celle-ci. Cette invention concerne également des procédés de fabrication et d'utilisation de ce produit combiné pour traiter divers états associés à des faibles niveaux de circulation des oestrogènes ou à une faible activité des récepteurs d'oestrogènes.

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