O-glucosylated benzamide sglt2 inhibitors and method

Details O-glucosylated benzamide sglt2 inhibitors and method O-glucosylated benzamide sglt2 inhibitors and method

C - Chemistry, Metallurgy

07

H

C07H 15/203 (2006.01) A61K 31/7034 (2006.01) A61P 7/12 (2006.01)

Patent

CA 2404376

SGLT2 inhibiting compounds are provided having the formula (I) wherein n is 0, 1 or 2; A is formula (a) or heteroaryl which may contain 1 to 4 heteroatoms in the ring which may be selected from N, O, S, SO, and/or SO2, bearing substituents R3 and R4; and R1 to R4 are as defined herein. A method is also provided for treating diabetes and related diseases employing an SGLT2 inhibiting amount of the above compound alone or in combination with one, two or more other antidiabetic agents and/or one, two or more hypolipidemic agents.

Composés inhibiteurs de SGLT2 qui correspondent à la formule (I) dans laquelle n est 0, 1 ou 2; A est la formule (a) hétéroaryle, qui peut contenir 1 à 4 hétéroatomes dans le noyau, qui peuvent être sélectionnés parmi N, O, S, SO et/ou SO2, comportant des substitutifs R3 et R4; et R1 à R4 sont définis dans l'invention. L'invention concerne aussi un procédé pour traiter le diabète et les maladies y liées en utilisant une quantité inhibitrice de SGLT2 du composé indiqué ci-dessus ou en combinaison avec un, deux ou plusieurs agents antidiabétiques et/ou un, deux ou plusieurs agents hypolipidémiques.

Affiliated with

Also associated with

Rating

O-glucosylated benzamide sglt2 inhibitors and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with O-glucosylated benzamide sglt2 inhibitors and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and O-glucosylated benzamide sglt2 inhibitors and method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1888280