O-(n-allyl-2,6-dichloroanilino) phenylacetic acid derivative...

C - Chemistry – Metallurgy – 07 – C

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260/514.1, 260/4

C07C 101/453 (1980.01) C07C 103/28 (1980.01) C07C 103/76 (1980.01)

Patent

CA 1146960

ABSTRACT OF THE DISCLOSURE: An o-(N-allyl-2,6-dichloroanilino)phenylacetic acid derivative represented by the formula: Image wherein R1, R2 and R3, which may be the same or different, individually represent a hydrogen atom, a halogen atom or an alkyl group having 1 to 4 carbon atoms; Y represents a hydroxyl group, an alkoxyl group, a -OM1 group in which M1 is an alkali metal atom, a Image group in which M2 is an alkaline earth metal atom, an amino group having the formule -NR5R5 in which R5 and R6, which may be the same or different, individually represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, or a hydroxylamino group, and a process for preparing the same. This derivative is useful as an intermediate for the preparation of the sodium salt of O-(2,6-dichloroanilino) phenylacetic acid which is known to have anti-inflammatory and analgesic activities.

336449

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