O-substituted hydroxycumaranone derivatives as antitumor and...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/79 (2006.01) A61K 31/37 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 307/83 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2296476

Compounds of formula (I) wherein R,R', A,B,T and x have the meaning given in the specification possess uPA (urokinase-type plasminogen activator) antagonist activity and can be employed as antitumor and/or antimetastatic agents.

Composés représentés par la formule (I) dans laquelle R,R', A,B,T et x possèdent la signification indiquée dans le descriptif, présentent une activité d'antagonistes d'uPA (activateur de plasminogène de type urokinase) et peuvent être mis en application en tant qu'agents antitumoraux et/ou antimétastatiques.

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