Ob protein binding protein

Details Ob protein binding protein Ob protein binding protein

A - Human Necessities

61

K

A61K 47/42 (2006.01) A61K 38/22 (2006.01) A61K 38/57 (2006.01) C07K 14/81 (2006.01) C07K 16/26 (2006.01) G01N 33/53 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2257474

A leptin binding protein, inter-alpha-trypsin inhibitor heavy chain related protein (IHRP), specifically binds leptin, the obesity gene product. The specific leptin binding proteins enable modulation of free leptin levels, immobilization and assay of bound/free leptin.

L'invention concerne une protéine de liaison à la leptine, protéine apparentée à la chaîne lourde de l'inhibiteur de la trypsine inter-alpha, qui fixe spécifiquement la lepsine, le produit génique de l'obésité. Les protéines spécifiques de liaison à la leptine permettent de moduler les taux de leptine libre, l'immobilisation et l'analyse de la leptine liée/libre.

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