Obesity associated biallelic marker maps

Details Obesity associated biallelic marker maps Obesity associated biallelic marker maps

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/09 (2006.01) G06F 17/30 (2006.01)

Patent

CA 2416559

The present invention relates to genomic maps comprising biallelic markers, new biallelic markers, and methods of using biallelic markers. Primers hybridizing to regions flanking these biallelic markers are also provided. This invention provides polynucleotides and methods suitable for genotyping a nucleic acid containing sample for one or more biallelic markers of the invention. Further, the invention provides a number of methods utilizing the biallelic markers of the invention including methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype.

La présente invention concerne des cartes génomiques comprenant des marqueurs bialléliques, de nouveaux marqueurs bialléliques, et des méthodes d'utilisation des marqueurs bialléliques. L'invention concerne également des amorces d'hybridation à des régions adjacentes auxdits marqueurs bialléliques. L'invention concerne en outre des polynucléotides et des méthodes adaptées au génotypage d'un échantillon contenant un acide nucléique pour un ou plusieurs marqueurs bialléliques de l'invention. De plus, l'invention concerne un certain nombre de méthodes dans lesquelles sont utilisés les marqueurs bialléliques de l'invention, y compris des méthodes de détection d'une corrélation statistique entre un allèle marqueur biallélique et un phénotype et/ou entre un haplotype marqueur biallélique et un phénotype.

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