Obesity markers and uses thereof

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2533667

The present invention relates to a method for identification of a nucleotide substitution in the gene encoding for the neuromedin- or quantifying its levels of mRNA, to allow the determination of the susceptibility or predisposition of a patient to obesity, or to disinhibition or susceptibility to hunger. Determination of the susceptibility or predisposition to obesity or to hunger disinhibition can alternatively be determined by the identification of an amino acid.

L'invention concerne un procédé permettant d'identifier une substitution nucléotidique dans le gène codant pour la neuromédine .beta. ou à quantifier les taux d'ARNm de celle-ci, afin de déterminer la tendance ou la prédisposition d'un patient à l'obésité ou à la désinhibition, ou la sensibilité à la faim de celui-ci. Dans un mode de réalisation, on détermine la tendance ou la prédisposition à l'obésité ou à la désinhibition par rapport à la faim en identifiant un acide aminé.

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