Occlusion compound of 2-nitroxymethyl-6- chloropyridine with...

Details Occlusion compound of 2-nitroxymethyl-6- chloropyridine with... Occlusion compound of 2-nitroxymethyl-6- chloropyridine with...

C - Chemistry, Metallurgy

08

B

167/202, 260/220

C08B 37/16 (2006.01) A61K 31/44 (2006.01) A61K 47/48 (2006.01) C08B 37/00 (2006.01)

Patent

CA 1248523

AN OCCLUSION COMPOUND OF 2-NITROXYMETHYL- 6-CHLOROPYRIDINE WITH .beta. -CYCLODEXTRIN AND PROCESS FOR PREPARATION THEREOF ABSTRACT OF THE DISCLOSURE 2-Nitroxymethyl-6-chloropyridine is known as an agent for the treatment of vascular disorders. Such agent is a volatile liquid, creating difficulty in its formulation into an acceptable pharmaceutical form. Occlusion compounds thereof with .beta.-cyclodextrin, preferably in the molar ratio of about 1:1 to 1:3, are powders of reduced volatility, and therefor have an enhanced application as pharmaceutical agents.

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