Octahydro-1h-benzo ¬4,5| furo ¬3,2-e| isoquinoline analgesic...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/048 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07D 307/81 (2006.01) C07D 491/10 (2006.01)

Patent

CA 1150263

ABSTRACT OF THE DISCLOSURE Octahydro-1H-benzo[4,5]furo[3,2-e]isoquinoline compounds and processes for their manufacture are provided. The compounds correspond to the formula Image These compounds exhibit both analgesic and narcotic antagonistic properties, as well as low abuse liability. Novel intermediate compounds are also provided which have the formula Image

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