Octahydro-2-h-naphtho[1,2-f] indole-4-carboxamide...

Details Octahydro-2-h-naphtho[1,2-f] indole-4-carboxamide... Octahydro-2-h-naphtho[1,2-f] indole-4-carboxamide...

C - Chemistry, Metallurgy

07

D

C07D 417/00 (2006.01) C07D 231/44 (2006.01)

Patent

CA 2499150

The present invention encompasses compounds of Formula I: or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.

La présente invention concerne des composés représentés par la formule (I) ou bien des sels ou des hydrates pharmaceutiquement acceptables de ces composés, qui conviennent en tant que ligands sélectifs de récepteur glucocorticoïde pour le traitement de diverses maladies et pathologies auto-immunes et inflammatoires. Sont également décrites des compositions pharmaceutiques et leurs méthodes d'utilisation.

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