Octahydro-indolizine compounds useful as analgesics

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01)

Patent

CA 1255306

OCTAHYDROINDOLIZINE COMPOUNDS USEFUL AS ANALGESICS ABSTRACT Octahydroindolizidines of the formula (1): Image (I) where A is a 3-7 carbon or hetero-containing ring, R1 is a substituent and x is 0-3. Also, pharmaceutical composition for treating pain and methods for synthesis and use as well as novel intermediates in the synthesis. MN 414

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