Octahydro-indolo [2,3-a] quinolizine compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 487/14 (2006.01)

Patent

CA 1108146

Abstract of the Disclosure New pharmacologically active octahydro-indolo[2,3-a]?ui- nolisine derivative of the formula: Image wherein Q in hydrogen or an A-CH2-CH2- group and A is cyano or -COOR, wherein R is C1-6 alkyl, are prepared by reacting 2,3,4,6,7,12-hexahydro-indolo[2,3-a]quinolizine with a compound of the formula CH2=CH-A, wherein A has the same meaning as above, and reducing the obtained hexahydro- -indolo[2,3-a] quinolizine derivative of the formula Image wherein A and Q have the same meaning as above.

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