C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/10 (2006.01) A61K 31/47 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2177046
The present invention relates to a composition, and method of use, of an octahydrobenzo[f]quinoline-based compound represented by structural formula (I). In this formula, R1 is -OH or -OCH3 and R2 is -H, -OH or -OCH3. In addition, R3 is a C1 to C2 saturated or unsaturated, alkyl group. Furthermore, R4 is an aryl group, wherein examples of suitable aryl groups, as defined herein, include phenyl and thienyl groups. The method of this invention relates to the use of the claimed compositions to treat psychotic disorders, to treat Parkinson's disease, or to sedate a mammal by administering an effective amount of a claimed composition.
La présente invention concerne une composition et un procédé d'utilisation d'un composé à base d'octahydrobenzo[f]quinoléine représenté par la formule développée (I). Dans cette formule, R?1¿ est un -OH ou un -OCH¿3? et R?2¿ est un -H, un -OH ou un -OCH¿3?. En plus, R?3¿ est un groupe alkyle saturé ou non en C1 ou en C2. En outre, R?4¿ est un groupe aryle. Comme exemples de groupes aryle appropriés, on peut citer les groupes phényle et thiényle. L'invention concerne également une méthode utilisant de telles compositions, administrées en une quantité appropriée, pour traiter des troubles psychotiques, la maladie de Parkinson ou pour calmer un mammifère.
Froimowitz Mark
Jacob James N.
Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations (the)
Borden Ladner Gervais Llp
Froimowitz Mark
LandOfFree
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