C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01)
Patent
CA 2572047
The present invention is related to octahydropyrrolo[2,3,c]pyridine derivatives of Formula (I) and use thereof in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.
La présente invention concerne des dérivés de octahydropyrrolo[2,3,c]pyridine représentés par la formule (I) et leurs utilisations en particulier pour le traitement et/ou la prophylaxie de pathologies auto-immunes, inflammatoires, cardiovasculaires, neurodégénératives, cancéreuses, respiratoires, de la fibrose, et notamment de la sclérose en plaque, l'arthrite, l'emphysème, la bronchopneumopathie chronique obstructive, et la fibrose hépatique et pulmonaire.
Bombrun Agnes
Swinnen Dominique
Applied Research Systems Ars Holding N.v.
Kirby Eades Gale Baker
Merck Serono Sa
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