Octahydroquinoli zines for antidiabetic treatment

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 455/02 (2006.01) A61K 31/4375 (2006.01) A61P 3/04 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2710006

This invention relates to novel octahydroquinolizines for treatment or prevention of diabetes mellitus and its complications, for treatment or prevention of hyperlipidemia, for treatment of diabetic dyslipidemia, for treatment or prevention of the metabolic syndrome, for treatment of diseases related to metabolic dysfunction, for treatment of obesity or obesity-related diseases. The invention also includes pharmaceutical compositions and kits comprising these compounds alone or in combination with other drugs or compounds aiming towards an improved treatment or prevention of the aforementioned diseases or syndromes in humans or animals.

L'invention concerne de nouvelles octahydroquinolizines utilisées dans le traitement ou la prévention du diabetes mellituset de ses complications, dans le traitement ou la prévention de l'hyperlipidémie, dans le traitement de la dyslipidémie diabétique, dans le traitement ou la prévention du syndrome métabolique, dans le traitement de maladies liées à un dysfonctionnement métabolique, et dans le traitement de l'obésité ou de maladies liées à l'obésité. L'invention se rapporte aussi à des compositions pharmaceutiques et à des trousses comprenant lesdits composés, seuls ou combinés à d'autres médicaments ou composés, qui ont pour objet d'offrir un traitement ou une prévention améliorés des maladies et syndromes précités chez des humains ou des animaux.

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