Octreotide-pamoate and its use in sustained release...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/06 (2006.01) A61K 38/08 (2006.01)

Patent

CA 2535463

The present invention is directed to octreotide-pamoate which is suitable for use in sustained release formulations of a peptide drug compound preferably a somatosatin like octreotide, e.g. as a pamoate salt. The drug compound is present in a polymeric carrier, preferably a polylactide-co-glycolide, especially a poly(lactide-co-glycolide)glucose. The formulation is preferably a depot formulation in the form of a monolithic microparticle.

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