Ocular hypotensive agent

Details Ocular hypotensive agent Ocular hypotensive agent

A - Human Necessities

61

K

A61K 31/41 (2006.01) A61K 9/06 (2006.01) A61K 31/395 (2006.01) A61K 31/415 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2127202

Abstract of the Disclosure This invention relates to an ocular hypotensive agent which comprises a compound represented by the formula: Image wherein R1 represents hydrogen or an optionally substituted hydrocarbon residue that may be bound via a hetero atom; R2 represents hydrogen or a hydrocarbon residue that may have a substituent; R3 represents a group capable of forming an anion or a group capable of changing thereto; X is a covalent bond between the 2 benzene rings or a spacer having a chain length of 1 to 2 atoms as the linear moiety between the adjoining phenylene group and phenyl group; n represents 1 or 2; ring A is a benzene ring having 1 or 2 optional substituents in addition to the group represented by COOR2, or a pharmaceutically acceptable salt thereof.

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