Ocular hypotensive agents

A - Human Necessities – 61 – K

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167/211

A61K 31/50 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2013912

ABSTRACT Pharmaceutical compositions for treatment of eye disorders employ ocular hypotensive compounds of the formula (I); Image (I) (wherein: R1 is selected from hydrogen, C1-C6 alkyl, and C1-C6 alkoxy; each R2 is selected from hydrogen, C1-C6 alkyl, halogen, nitro or carboxy; R3 is selected from heterocyclic, amino, mono-substituted amino, and di-substituted amino, A and B each represents C1-C6 alkylene, X represents -NH- or -CH2-; and n is 1, 2 or 3) or pharmaceutically acceptable salts or esters thereof.

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