Ocular therapy using glucocorticoid derivatives selectively...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2602577

Ophthalmically therapeutic materials, such, as liquid- containing compositions and polymeric drug delivery systems, include a therapeutic component that includes an Glucocorticoid Derivative which, upon delivery to the posterior segment of a mammalian eye, does not significantly diffuse to the anterior segment of said eye. Methods of making and using the present materials are also described.

Des matières thérapeutiques du point de vue ophtalmique, telles que des compositions contenant un liquide et des systèmes d'apport de médicaments polymères, comprennent un constituant thérapeutique qui inclut un dérivé de glucocorticoïde qui, lors de sa livraison à un segment postérieur d'un oeil de mammifère, ne se diffuse pas significativement vers le segment antérieur dudit oeil. Des procédés de préparation et d'utilisation des matières selon l'invention sont également présentés.

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