Ocular therapy using sirtuin-activating agents

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2643903

Ophthalmically therapeutic compositions, such as polymeric drug delivery systems, include a therapeutic component that includes a sirtuin-activating agent, such as resveratrol, which, upon delivery to the posterior segment of a mammalian eye, treats ocular conditions. Methods of making and using the present compositions are also described.

L'invention concerne des compositions thérapeutiques ophtalmiques, telles que des systèmes de libération de médicaments polymères, contenant un composant thérapeutique qui contient un agent activateur de la sirtuine, tel que le resveratol, qui traite les affections oculaires par libération sur la partie postérieure de l'oeil d'un mammifère. L'invention concerne également des procédés de fabrication et des méthodes d'utilisation de ces compositions.

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