C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61P 27/06 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2386177
Nucleic acids encoding oculomedin polypeptide are disclosed. Also described are related nucleic acids encoding oculomedin polypeptides, oculomedin polypeptides; antibodies that bind to oculomedin polypeptides, methods of diagnosis of glaucoma; assays for agents that alter the activity of oculomedin polypeptide or which identify oculomedin binding partners or assess the strength of an interaction between oculomedin and an oculomedin binding partner, and the agents or binding partners identified by the assays; pharmaceutical compositions comprising the oculomedin nucleic acids, oculomedin polypeptides, or agents that alter the activity of the oculomedin polypeptides; as well as methods of therapy of glaucoma.
Cette invention se rapporte à des acides nucléiques codant un polypeptide d'oculomédine. Cette invention concerne également des acides nucléiques apparentés codant des polypeptides d'oculomédine; des polypeptides d'oculomédine; des anticorps qui se fixent à des polypeptides d'oculomédine; des procédés de diagnostic du glaucome; des dosages de détection d'agents qui modifient l'activité d'un polypeptide d'oculomédine ou qui identifient des partenaires de fixation d'oculomédine ou évaluent l'intensité d'une interaction entre l'oculomédine et un partenaire de fixation d'oculomédine, et les agents ou partenaires de fixation identifiés par ces dosages; des compositions pharmaceutiques contenant ces acides nucléiques d'oculomédine, ces polypeptides d'oculomédine ou ces agents qui modifient l'activité des polypeptides d'oculomédine; ainsi que des procédés de thérapie du glaucome.
Gowling Lafleur Henderson Llp
Matsuo Toshihiko
LandOfFree
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