Oil body associated protein compositions and methods of use...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/415 (2006.01) A23L 1/30 (2006.01) A23L 1/305 (2006.01) A61K 38/16 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2482464

Compositions and methods for reducing hypercholesterolemia and, accordingly, the risk of cardiovascular disease, are provided. Such compositions may comprise isolated oil body associated proteins. Additionally provided are foodstuffs to which one or more oil body associated proteins have been added. The compositions employed in the invention may further comprise additive compounds, for example, a saponin, an isoflavone, a phospholipid, a carbohydrate substantially resistant to digestion, or a combination thereof. The methods and compositions of the invention may be used to lower cholesterol and other lipid levels in subjects to achieve a reduction in the risk of cardiovascular disease.

L'invention concerne des compositions et des méthodes permettant de diminuer l'hypercholestérolémie, et, par conséquent, le risque de maladie cardio-vasculaire. De telles compositions peuvent renfermer des protéines isolées associées à un corps lipidique. En outre, ladite invention a trait à des aliments auxquels a été ajoutée au moins une protéine associée à un corps lipidique. Les compositions employées dans cette invention peuvent contenir des composés additifs, par exemple, une saponine, une isoflavone, un phospholipide, un glucide résistant à la digestion ou un mélange correspondant. Ces méthodes et ces compositions peuvent être utilisées pour abaisser le taux de cholestérol et les autres taux de lipides chez des sujets, de manière à diminuer le risque de maladie cardio-vasculaire.

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