A - Human Necessities – 23 – D
Patent
A - Human Necessities
23
D
A23D 7/01 (2006.01) A61K 9/107 (2006.01)
Patent
CA 2687367
The present invention concerns the use of an oil-in-water emulsion where the interior of oil droplets exhibit interfaces, between lipophilic domains and hydrophilic or amphiphilic domains, due to the presence of a lipophilic additive solubilized inside the oil droplets and which is used for delayed release of active elements such that the release of at least one active element, which has a octanol/water partitioning coefficient logP higher than - 1, corresponds to a higher Tmax than the Tmax obtained for the simple reference oil-in-water emulsion where no lipophilic additive is used.
La présente invention concerne l'utilisation d'une émulsion huile-dans-eau dans laquelle l'intérieur des gouttelettes présente des interfaces entre les domaines lipophiles et les domaines hydrophiles ou amphiphiles par suite de la présence d'un additif lipophile solubilisé dans les gouttelettes utilisé pour la libération différée d'éléments actifs, de telle sorte que la libération d'au moins un élément actif à coefficient de fractionnement octanol/eau logP supérieur à -1 correspond à un Tmax plus élevé que le Tmax de la simple émulsion huile-dans-eau de référence sans additif lipophile.
Godinot Nicolas
Leser Martin
Phan Van Anh
Robert Fabien
Sagalowicz Laurent
Borden Ladner Gervais Llp
Nestec S.a.
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