Oil-in-water emulsions containing lignan-class compounds and...

A - Human Necessities – 61 – K

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Details

A61K 31/36 (2006.01) A23L 1/30 (2006.01) A61K 9/107 (2006.01) A61K 47/24 (2006.01) A61K 47/44 (2006.01) A61P 1/16 (2006.01) A61P 3/06 (2006.01) A61P 11/06 (2006.01) A61P 25/32 (2006.01) A61P 25/34 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2603347

The purpose is to increase the rate of uptake of a lignane compound in the body, that is, to provide a lignane compound having a quick-acting property. A lignane compound-containing composition comprising an oil-in-water emulsion having an aqueous phase and an oil phase (in which at least one lignane compound to be dissolved in an oil) emulsified in the aqueous phase, oil droplets corresponding to the dispersed phase being finely divided by high speed stirring or the like so that the average particle size of the oil droplets is adjusted to 1000 nm or smaller, preferably 500 nm or smaller, more preferably 300 nm or smaller. This composition permits the lignane compound to be absorbed in the body more rapidly and to exert its effect quickly.

L'invention concerne l'augmentation du taux d'assimilation d'un composé de lignane dans le corps, à savoir, la génération d'un composé de lignane à action rapide. Une composition renfermant un composé de lignane contient une émulsion huile-eau possédant une phase aqueuse et une phase huileuse (dans laquelle au moins un composé de lignane doit être dissous dans une huile) émulsifiée dans la phase aqueuse. Des gouttelettes d'huile correspondant à la phase dispersée sont finement divisées par mélange à vitesse élevée ou similaire, de telle manière que la taille particulaire moyenne des gouttelettes d'huile est adaptée à 1000 nm au maximum, de préférence à 500 nm voire moins, et idéalement à 300 nm tout au plus. Cette composition permet au composé de lignane d'être absorbé dans le corps plus rapidement et d'exercer son effet rapidement.

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