C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/55 (2006.01) C07D 243/00 (2006.01) C07D 333/00 (2006.01)
Patent
CA 2464306
The present invention relates to novel dihydrate form of 2-methyl-4-(4-methyl- 1-piperazinyl)-10Hthieno[2,3-b][1,5]benzodiazepine (hereinafter referred to as Olanzapine dihydrate-II), a process for its preparation and its conversation to Olanzapine Form-II. The present invention also relates to compositions containing Olanzapine dihydrate II and the use of Olanzapine dihydrate II and compositions containing Olanzapine dihydrate II for treating disorders of the central nervous system.
L'invention concerne une nouvelle forme de dihydrate 2-methyl-4-(4-methyl-1-piperazinyl)-10<I>H</I>-thieno[2,3-b][1,5 benzodiazepine (appelé dihydrate-II d'olanzapine), son procédé de préparation et sa conversion en olanzapine de forme II. L'invention concerne également des compositions contenant le dihydrate-II d'olanzapine, l'utilisation dudit dihydrate-II d'olanzapine et des compositions contenant le dihydrate-II d'olanzapine permettant de traiter des troubles du système nerveux central.
Ramesh Chakka
Reddy Reguri Buchi
Dr. Reddy's Laboratories Ltd.
Marks & Clerk
LandOfFree
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