Oligodeoxyribonucleotides of 4000-10000 dalton for treating...

A - Human Necessities – 61 – K

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A61K 31/711 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2598072

The use of oligodeoxyribonucleotides having a molecular weight of 4000-10000 Dalton as an anti-tumour agent, alone or in combination with other active ingredients with anti-tumour action, is described. The oligotide may be produced by extraction from animal and/or vegetable tissues, in particular, from mammalian organs, or may be produced synthetically. The tumors which can be treated are preferably angiogenesis- dependent tumors, such as multiple myeloma or breast carcinoma.

L'invention concerne l'utilisation d'oligodésoxyribonucléotides présentant un poids moléculaire compris entre 4000 et 10000 daltons en tant qu'agents antitumoraux, seuls ou en combinaison avec d'autres ingrédients actifs à action antitumorale. L'oligotide de l'invention peut être obtenu par extraction à partir de tissus animaux et/ou végétaux, en particulier à partir d'organes de mammifères, ou peut être produit de manière synthétique. Les tumeurs pouvant être traitées sont de préférence des tumeurs dépendantes de l'angiogenèse, de type myélome multiple ou cancer du sein.

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