Oligomer-antihistamine conjugates

Details Oligomer-antihistamine conjugates Oligomer-antihistamine conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 37/08 (2006.01) C07C 217/10 (2006.01) C07D 295/088 (2006.01) C08G 65/333 (2006.01) A61K 31/138 (2006.01) A61K 31/496 (2006.01)

Patent

CA 2679070

The invention provides antihistamine drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the antihistamine drug not attached to the water-soluble oligomer.

L'invention concerne des médicaments antihistaminiques chimiquement modifiés par une fixation covalente d'un oligomère hydrosoluble. Un conjugué de l'invention, lorsqu'administré par une quelconque d'un certain nombre de voies d'administration, présente des caractéristiques qui sont différentes des caractéristiques du médicament antihistaminique non lié à l'oligomère hydrosoluble.

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