C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2390312
The invention relates to an oligomer array with PNA (Peptide Nucleic Acid) and/or DNA oligomers on a surface, said oligomers comprising oligomers of 6 to 20 monomers or nucleobases each. Said monomers or nucleobases comprise at least one sequence of the general formula DDCGDD or of the general formula DDTGDD or of the general formula HHCGHH or of the general formula HHCAHH, wherein H represents any of the bases adenine (A), cytosine (C) or thymine (T) and D represents any of the bases adenine (A), guanine (G) or thymine (T). The location of the oligomers on the surface is correlated with the sequence of the oligomers. The inventive oligomer arrays are used to detect cytosine methylations in genomic DNA.
L'invention concerne un réseau oligomère comportant des oligomères de PNA (acides nucléiques peptidiques) et/ou d'ADN sur une surface, contenant des oligomères composés de 6 à 20 monomères ou bases nucléiques comportant au moins une séquence de formule générale DDGCDD, DDTGDD, HHCGHH, ou HHCAHH, H étant une des bases adénine (A), cytosine (C) ou thymine (T), D étant une des bases adénine (A), guanine (G) ou thymine (T), et la position des oligomères sur la surface étant corrélée avec la séquence des oligomères. Les réseaux oligomères selon l'invention sont utilisés pour la détection de méthylations de cytosine dans l'ADN génomique.
Epigenomics Ag
Macrae & Co.
LandOfFree
Oligomer array with pna and/or dna oligomers on a surface does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oligomer array with pna and/or dna oligomers on a surface, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oligomer array with pna and/or dna oligomers on a surface will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1820184