Oligomer-opioid agonist conjugates

Details Oligomer-opioid agonist conjugates Oligomer-opioid agonist conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2679479

The invention provides opioid agonists that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the opioid agonist not attached to the water-soluble oligomer.

L'invention concerne des composés chimiquement modifiés par une fixation covalente d'un oligomère hydrosoluble. Un composé de l'invention, lorsqu'administré par une quelconque d'un certain nombre de voies d'administration, présente des caractéristiques différentes de celles du composé non lié à l'oligomère hydrosoluble.

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